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Dr. Chalermchai summarizes 5 points: The new 2-strain COVID vaccine is not as effective as expected.

Not as expected Dr Chalermchai summarized 5 points: The new 2-strain COVID vaccine stimulates immunity better than the first vaccine, but not by much, noting that the maximum efficiency in younger people is only 56% . the better the results.

Today (December 5, 2022), Dr Chalermchai Boonyaleephan posted a private blockdit “one hundred and eight thousand and nine with Doctor Chalermchai” about the new vaccine, stating that he was disappointed!! Both brands of new two-strain vaccines using mRNA technology did not fare as well as expected.

It is well known that the coronavirus that causes COVID-19 has mutated in sequence. starting with the Wuhan virus strain

And in the next 11 months, many countries succeeded in developing a vaccine against COVID. using the Wuhan virus as a starting point And it works very well, at an effectiveness level of 70 to 95%. So, there are many rapid mutations. Speaking of just the main types, VOC: Variant of Concern will have alpha, beta, gamma, delta and omikron. Failing to accelerate research and development to keep up with the species mentioned above

Until the year 2022, the Omicron virus has been the main species that can stand for a year giving scientists enough time to successfully develop a second generation 2-strain vaccine by combining the Wuhan strain with the Omicron strain of subspecies BA.4/5, which in the United States It was introduced a few months ago and the USCDC collected data between September 14 and November 11, 2022 on 360,000 vaccine recipients. It is mRNA technology (mRNA), two famous brands and injected into people who have injected one type of old vaccine before. Whether it’s two needles, three needles or four needles, find an interesting number that The further it is injected from the original vaccine, the more it will only get more immunity and injections in young people get higher immunity than injections in the elderly

The numbers are that if injected 2-3 months away from the original vaccine, the effectiveness will increase by 28-31% compared to not vaccinating the new version. But if the new booster vaccine is given more than 8 months apart, the effectiveness increases to 43-56%.
43% over 65 years of age
48% among people aged 50-64
56% among 18-49 year olds

In summary, 1. The so-called new second-generation two-strain vaccine contains the Wuhan virus strain and the Omikron virus strain. substrain BA 4/5 2. The efficacy of the second generation two-layer booster vaccine was slightly better than the first generation vaccine. When injected 8 months apart from the original, it will work better than injecting 2-3 months apart 4. Immunity will be higher from vaccination in people aged 18-49 than in people aged 50 and over and 5 a second It did not give high efficacy at the level of 70-95% as in the production of the first vaccine, 1st generation to deal with the Wuhan virus.